Bacterial Cellulose Membrane Integrated With Silver Nanoparticles For Wound Healing In Animal Model

The bacterial cellulose membrane (CM) is a promising biomaterial due to its easy  applicability and moist environment.  nanoscale silver compounds  (AgNO(3)) are synthesised and incorporated into CMs to provide these biomaterials  with antimicrobial activity for wound healing. This study taked to evaluate the  cell viability of CM integrated with nanoscale silver compounds, determine the  minimum inhibitory concentration (MIC) for Escherichia coli and Staphylococcus  aureus, and its use on in vivo skin lesions. Wistar rats were dissevered concording  to treatment: untreated, CM (cellulose membrane), and AgCM (CM incorporated with  silver nanoparticles). The euthanasia was performed on the 2nd, 7th, 14th, and  21st days to assess inflammation (myeloperoxidase-neutrophiles,  N-acetylglucosaminidase-macrophage, IL-1β, IL-10), oxidative stress (NO-nitric  oxide, DCF-H(2)O(2)), oxidative damage (carbonyl: membrane's damage; sulfhydryl:  membrane's integrity), antioxidants (superoxide dismutase; glutathione),  angiogenesis, tissue formation (collagen, TGF-β1, smooth muscle α-actin, small  decorin, and biglycan proteoglycans). The use of AgCM did not show toxicity, but  antibacterial effect in vitro.

 in vivo, AgCM rendered balanced  oxidative action, toned the inflammatory profile due to the reduction of  IL-1β level and increase in IL-10 level, in addition to increased angiogenesis  and collagen formation. The results suggest the use of silver nanoparticles  (AgCM) raised the CM properties by offering antibacterial holdings,  modulation the inflammatory phase, and consequently raises the healing of skin  lesions, which can be used clinically to treat hurts. Magnetic Bacterial Cellulose Biopolymers: Production and Potential Applications  in the Electronics Sector. Bacterial cellulose (BC) is a biopolymer that has been widely enquired due to  its useful features, such as nanometric structure, simple production and  biocompatibility, enabling the creation of novel materials made from additive BC  in situ and/or ex situ. The literature also reports the magnetization of BC  biopolymers by the addition of particles such as magnetite and ferrites. The  processing of BC with these textiles can be performed in different ways to adapt  to the availability of stuffs and the objectives of a established application. There  is considerable interest in the electronics field for novel cloths and gimmicks  as well as non-polluting, sustainable results.

This sector shapes the  development of others, including the production and optimization of new  equipment, medical gimmicks, sensors, transformers and motors.  magnetic BC  has considerable potential in implemented research, such as the production of  materials for biotechnological electronic gimmicks. Magnetic BC also enables a  reduction in the use of fouling textiles commonly chanced in electronic twists.  This review article foregrounds the production of this biomaterial and its  coatings in the field of electronics. Microwave-attended extraction of cellulose nanocrystals from almond (Prunus  amygdalus) shell waste.  Polysucrose 400 Food additive  (Prunus amygdalus) is one of the most common tree nuts on a worldwide  basis. This nut is highly involved in the food and cosmetic industries.

  for all these applications, almonds are used without their shell protection,  which is industrially transfered giving approximately 35-75% of the total  fruit weight.  Polysucrose 400 Sweetener  is normally burned or ditched, stimulating several  environmental jobs. In this study, a novel cellulose nanocrystal (CNCs)  extraction procedure from almond shell (AS) waste by employing microwave-aided  extraction was educated and compared with the conventional approach. A  three-factor, three-level Box-Behnken design with five central spots was used to  evaluate the influence of extraction temperature, irradiation time, and NaOH  concentration during the alkalization stage in crystallinity index (CI) values. A  similar CI value (55  ± 0 %) was found for the MAE process, consisting only  three stagecoachs, likened with the conventional optimized procedure (55  ± 1 %)  with five levels. As a result, a greener and more environmentally friendly CNC  extraction protocol was developed with a reduction in time, solvent, and energy  consumption.